Comprehensive Method Development
and Validation Services |
Reliable Product Characterization
and Quality Control Testing |
 Western blot |
| Identity: AAA and peptide mapping |
| Protein content |
| Sequence: peptide mapping |
| Immunoassays |
| Genetic stability: peptide mapping |
| Purity/Potency |
| Glycosylation: colorimetric assays, CE |
| Activity: protein/enzyme assays |
| Impurity analysis: SDS-PAGE, HPLC |
| Disulfide bonds: Thannhauser method |
| Determination of extinction coefficients |
| Common impurities and contaminants |
|
| Residual protein and residual chemical analyses |
| Amino acid analysis |
| Gel electrophoresis: SDS-PAGE and horizontal agarose |
| Capillary electrophoresis |
| SDS-gel M.W. analysis |
| IgG purity |
| Isoelectric focusing (IEF) |
| Carbohydrate analysis |
| Peptide mapping |
| Chromatographic techniques |
| Protein content assay |
| Host cell proteins |
| Residual and total DNA |
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